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Volume 39 , Issue 4
July/August 2019
Pages 537–543

Treatment of Periodontal Intrabony Defects Using Enamel Matrix Derivative: Surgical Reentry After an Observation Period of at Least 5 Years

Vincenzo Iorio-Siciliano, DDS, PhD/Andrea Blasi, DDS, PhD/Paolo Nuzzolo, DDS/Marco Matarasso, DDS, PhD/Gaetano Isola, DDS, PhD/Luca Ramaglia, MD, DDS

PMID: 31226192
DOI: 10.11607/prd.4148

The purpose of this study was to assess the healing of periodontal intrabony defects treated using enamel matrix derivative (EMD) after at least 5 years of follow-up. Six patients with seven intrabony defects were included in the study. Treatment with EMD yielded a mean clinical attachment level gain of 4.3 ± 2.4 mm, a mean probing depth reduction of 4.7 ± 2.1 mm, and a mean gingival recession increase of 0.7 ± 1.8 mm. Reentry measurements showed a complete resolution of the intrabony defect in five cases, while in two cases a residual intrabony component was recorded. The present study indicates that treatment using EMD provided good clinical outcomes maintained in most cases over a period of at least 5 years.

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